Highlights from

WCD 2019

World Congress of Dermatology

Milan 10-15 June 2019

What the future of keloid treatment could hold

Less explored therapies include procedures with injection-free drug delivery that may gain further importance in the armamentarium for keloid treatment [1].

A new method of treatment application that has recently been investigated is thermomechanical drug delivery into keloid skin [2]. In a retrospective study, 7 patients were given a mix of triamcinolone acetonide (TAC) plus 5-fluorouracil in a ratio of 1:9 after skin treatment with a titanium tip heated to 400°C. After 8 topical thermal ablations (1 ablation performed every 2-3 weeks), mean keloid Vancouver Scar Scale score was significantly reduced from 8.6 ± 1.2 at baseline to 5 ± 2.7 (P=0.001) [2]. “As a principle after surgery of a keloid of the earlobe, the wound should be closed without tension,” said Dr Somesh Gupta (All India Institute of Medical Sciences, India) in his lecture on less explored and experimental treatments for keloids. Injections, pressure, or a combination of both are possible options to avoid recurrence after surgery, according to Dr Gupta [1]. “In general, we do not give injections because they are painful. We often prefer to use pressure earrings using neodymium magnetic discs,” he continued. This easy and economically available possibility should be applied for about 5-6 hours a day, in order to avoid necrosis.

  1. Gupta S. 24th World Congress of Dermatology, 10-15 June 2019, Milan, Italy.
  2. Artzi O, et al. Dermatol Ther. 2019;9:321-326.

Top image: @ iStockPhoto: AzmanL

The content and interpretation of these conference highlights are the views and comments of the speakers/authors.