Highlights from

ELCC 2019

European Lung Cancer Conference

Geneva 10-13 April 2019

Electromagnetic navigation: an instant hit?

NAVIGATE is the largest prospective, multicentre study to date evaluating electromagnetic navigation bronchoscopy (ENB). Results presented at the ELCC 2019 suggest that ENB provides a safe platform to aid in lung lesion biopsy.

ENB is an image-guided approach to access peripheral pulmonary lesions. It provides an integrated and efficient approach to aid in diagnosis of peripheral lesions, tissue collection for molecular testing, staging in the same procedure, and localisation for minimally invasive treatment.

1-month interim analysis

The NAVIGATE study evaluates the use of ENB in community and academic settings. Dr Kelvin Lau (St Bartholomew’s Hospital, London, United Kingdom) presented the data of a prespecified 1-month interim analysis of 175 subjects who were enrolled in Europe. This intervention was used in a challenging patient population: 67% with bronchus sign, 54% with lesions of <20 mm, and 73% with peripheral lesions.

Safe and fast

Results suggest that ENB provides a safe intervention. The complication rates were low. An intervention was required in 5% of pneumothorax cases. Also, the navigation success rate was high (96.6%) despite low use of concurrent imaging guidance (4% rEBUS, 10% CBCT, and 42% fluoroscopy). The median procedure time was only 40 minutes in total and 29 minutes for ENB navigation and sampling.

Conclusions

According to Dr Lau, these results from the European cohort of the NAVIGATE study suggest that ENB provides a safe platform to aid in lung lesion biopsy. ENB also allows multidimensional lung lesion biopsy, fiducial placement, and concurrent lymph node sampling during a single anaesthetic event.

  1. Lau K. Electromagnetic navigation bronchoscopy in the European cohort of the prospective, multicenter NAVIGATE study. ELCC 2019, Geneva, Switzerland; abstract 68O.

The content and interpretation of these conference highlights are the views and comments of the speakers/authors.